Formulation: Research and Contract Supply
More Reyra Trading Company provides research and contract supply services specializing in fermentation- and semi-synthetic-based commercial products. The company’s research and development (R&D) center, certified by DSIR (Department of Scientific and Industrial Research), consists of three divisions:
R&D Fermentation
The facility includes capabilities for strain isolation, mutation, and passive selection of microbial strains; shake flask systems for strain improvement; laboratory fermenters; and a pilot plant for scaling up fermentation processes.
Research and contract supply services in the field of fermentation are as follows:
- Strain improvement program aimed at significantly boosting the titer of the target product and/or refining its impurity profiling.
- Media optimization: Utilization of cost-effective, locally sourced client media to enhance overall process productivity.
Process Development: Optimizing process control during scaling to achieve high-yield and cost-effective production.
- Process scale-up from shake flask to pilot and commercial scales.
- Development of optimized biotransformation processes.
- Continuous improvement of processes.
R&D has state of the art facility for extraction, isolation and purification of product from upstream (fermentation) process. The facility is having a scaled down version of all the major equipment at plant, thus giving high flexibility during process scale up. R&D facility is equipped with all essential equipment for complex organic synthesis chemistry. Some of the major equipment are various filtration units like Micro filtration, Ultra filtration and Nano filtration, Open column chromatography, and filtration systems.
Some of the major activities at Chemical R&D are:
- Development of Downstream process to support upstream process.
- Process optimization and scale up of processes from R&D to pilot and commercial.
- Continuous process improvement to improve the overall process yield and have a cost effective process.
The analytical laboratory conducts the following operations:
- Synthesis, isolation, and characterization of process impurities.
Competitive advantages of partnering with More Reyra as a CRAM provider:
- Expertise with diverse strains such as Actinomycetes, Streptomycetes, Bacteria, Fungi, E. coli, and various biocatalyst classes.
- High capability in producing complex and specialized biotechnology products.
- Infrastructure capable of scaling processes from R&D through pilot to commercial stages.
- Research team led by senior scientists with Ph.D.s, microbiologists, and biotechnologists, offering extensive experience in biotechnology and downstream processes, ensuring timely project completion.
- Dedicated project teams.
- Robust R&D supported by analytical and regulatory expertise.
- Competitive pricing.
Our strengths in microbial fermentation, chromatography purification, and semi-synthetic chemistry make us the preferred partner for leading biopharmaceutical companies for CRAM (Contract Research and Manufacturing) opportunities in new fermentation and semi-synthetic small molecules.