Introduction (Article introduction authored by ICU Editorial Team) Improving the diagnosis of sepsis in newborns is crucial given their extended life expectancy, yet early detection remains challenging. A breakthrough has emerged with the development of a micromotor-based dual aptamer assay.

This innovative approach concurrently detects biomarkers like procalcitonin (PCT) and interleukin-6 (IL-6), significantly enhancing diagnostic precision essential for timely intervention.

Importantly, this method requires only a minute sample and provides results within just 15 minutes, revolutionizing neonatal sepsis diagnosis.

Its exceptional sensitivity and correlation with established hospital methods highlight its reliability, positioning it as a promising tool for promptly identifying sepsis in high-risk newborns.

The micromotor technology marks a new era in diagnostics based on low sample volumes, representing a paradigm shift in neonatal care. Its capability to deliver rapid and accurate results with minimal sample requirements makes it transformative in diagnosing neonatal sepsis.

By enabling swift decisions on initiating antibiotic therapy, this approach empowers clinicians to intervene effectively during the critical early stages of sepsis, potentially saving lives and improving outcomes for vulnerable newborns.

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